TABLE 3.

Most common amino acid mutations observed in all eight segments of A/H3N2.

MP	NP	NS	PA	HA	NA	PB1	PB2
V7I	I136M	R41K	L78I	G53D	E119X	K327X	M81I
G16E	V100I	S212P	N409X	E83K	Y155H	N328X	S107D
V27I	I136M	K217E	A100X	D104G	E221D	T57I	K340R
D30S	V197I	R224G	E119X	I140M	S245X	R586K	M410V
L43T	E220D	A226I	K158R	S205F	A246X	A587T	I461V
R77Q	P283X	R227G	N272S	A212T	S247X	L598X	R526K
N82S	K293X	S228T	I348L	K276R	G248X	E618D	I588T
S89G	Y313V	K229E	V354I		N329S		T613A
R101K	N373T	V230I	D396E		S367N		T711N
N133X	L418I		S402T		E368X
T139X	S450G		N409X		N402D
H159X	T472A		T515X		D463N
			V668I
			N675K