TABLE 2.

Phenotypic comparison of NK1- and HGF/SF-transgenic mice

Mouse type	Increase in liver mass (fold)	Elevation in hepatocyte proliferation (fold)	Severity of:						Incidence of:
			Renal disease		Olfactory mucosal degeneration	Ectopic skeletal muscle	Mammary hyperplasia	Patterned hyperpigmentation	Tumors			Met activation in liver
			Glomerulosclerosis	Tubular hyperplasia					Mammary adenocarcinoma	Melanoma	Liver adenoma
NK1	1.4	3.7	Moderate	Moderate	Mild	Moderate	Moderate	Moderate	Present	Present	Present	Present
HGF/SFa	2.0b	11c	Severe	Severe	Moderate	Moderate	Severe	Severe	High	High	Present	Present

^aExcept as noted, data are from references 27 and 33 to 35. 

^bDatum is from reference 27 for MH-19 mice aged 5 weeks and older. 

^cDatum is from reference 27 for MH-19 mice aged 4.7 weeks.