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. 2024 Feb 9;15:1323994. doi: 10.3389/fendo.2024.1323994

Table 1.

Baseline characteristics of participants according to TGAb, TPOAb status in the National Health and Nutrition Examination Survey, 2007 to 2012.

Characteristics TGAb (+) TPOAb (+)
No Yes p No Yes p
Participants, No. 6906 (92.46) 525 (7.54) / 6625 (88.52) 806 (11.48) /
Age, mean (SD) 46.42 (0.50) 52.80 (1.03) <0.01 46.31 (0.50) 51.46 (0.79) <0.01
Gender
Male 3526 (50.11) 204 (36.61) <0.01 3450 (50.92) 280 (34.98) <0.01
Female 3380 (49.89) 321 (63.39) 3175 (49.08) 526 (65.02)
Race
Mexican American 1062 (7.77) 80 (5.13) <0.01 1013 (7.85) 129 (5.46) <0.01
Non-Hispanic White 3253 (69.77) 294 (77.41) 3099 (69.06) 448 (80.19)
Non-Hispanic Black 1412 (10.76) 53 (4.32) 1375 (11.00) 90 (4.63)
Other 1179 (11.70) 98 (13.14) 1138 (12.08) 139 (9.72)
Education status
Under high school 1937 (17.76) 143 (14.56) 0.12 1882 (18.17) 198 (12.45) 0.01
High school or equivalent 1615 (22.69) 103 (19.58) 1529 (22.39) 189 (22.96)
Above high school 3354 (59.56) 279 (65.86) 3214 (59.44) 419 (64.60)
Poverty rartio
<=1 1498 (15.07) 93 (12.22) 0.13 1449 (15.29) 142 (11.48) 0.01
1<to<=3 2965 (36.72) 230 (32.12) 2850 (36.88) 345 (32.52)
>3 2443 (48.21) 202 (55.66) 2326 (47.83) 319 (56.00)
Smoking
Never 3636 (53.71) 293 (62.89) <0.01 3481 (53.87) 448 (58.50) <0.01
Ever 1747 (24.67) 147 (24.68) 1665 (24.28) 229 (27.64)
Current 1523 (21.62) 85 (12.43) 1479 (21.84) 129 (13.86)
BMI, mean (SD) 28.68 (0.15) 28.62 (0.47) 0.90 28.68 (0.16) 28.60 (0.43) 0.84
18.5≤BMI<25 118 (1.64) 8 (2.14) 0.87 111 (1.56) 15 (2.58) 0.49
BMI<18.5 1915 (30.04) 156 (30.78) 1851 (30.11) 220 (29.91)
BMI≥25 4873 (68.32) 361 (67.09) 4663 (68.32) 571 (67.51)
Diabetes
No 6096 (91.48) 452 (86.06) 0.01 5851 (91.32) 697 (89.17) 0.26
Yes 806 (8.48) 73 (13.94) 770 (8.64) 109 (10.83)
Missing or unknown 4 (0.04) 0 (0) 4 (0.04) 0 (0)
Hypertension
No 4467 (69.19) 332 (69.54) 0.83 4306 (69.52) 493 (66.89) 0.40
Yes 2432 (30.75) 193 (30.46) 2313 (30.43) 312 (33.06)
Missing or unknown 7 (0.06) 0 (0) 6 (0.06) 1 (0.05)
Cardiovascular disease
No 6185 (92.13) 459 (89.47) 0.20 5938 (92.26) 706 (89.33) 0.12
Yes 721 (7.87) 66 (8.60) 541 (7.74) 72 (10.67)
Arthritis
No 4969 (76.11) 347 (69.73) 0.04 4779 (76.20) 537 (71.20) 0.06
Yes 1925 (23.70) 176 (29.99) 1836 (23.65) 265 (28.22)
Missing or unknown 12 (0.19) 2 (0.29) 10 (0.15) 4 (0.58)
Chronic lung disease
No 5670 (82.09) 436 (83.32) 0.69 5441 (81.75) 665 (85.50) 0.06
Yes 1236 (17.91) 89 (16.68) 1184 (18.25) 141 (14.50)
Cancer
No 6252 (90.63) 460 (89.50) 0.15 5995 (90.54) 717 (90.63) 0.04
Yes 648 (9.30) 63 (10.13) 625 (9.42) 86 (8.96)
Missing or unknown 6 (0.06) 2 (0.37) 5 (0.04) 3 (0.40)
TSH
≤0.34 142 (1.67) 24 (4.45) <0.01 128 (1.54) 38 (4.49) <0.01
0.34<to<5.6 6642 (96.70) 448 (85.39) 6402 (97.23) 688 (85.25)
≥5.6 122 (1.63) 53 (10.16) 95 (1.23) 80 (10.26)
eGFR, mean (SD) 95.17 (0.62) 88.08 (1.24) <0.01 95.27 (0.60) 89.74 (0.87) <0.01
≥60 6319 (94.23) 461(90.95) 0.01 6063 (94.20) 717 (92.32) 0.10
<60 587 (5.77) 64 (9.05) 562 (5.80) 89 (7.68)

SD, standard deviation; BMI, body mass index; TSH, thyroid stimulating hormone; eGFR, estimated glomerular filtration rate.