Table 3.
Associations between different TGAb, TPOAb status and all-cause mortality in the National Health and Nutrition Examination Survey, 2007 to 2012 followed up through 2019.
| Characteristics | Univariate | Multivariate* | ||
|---|---|---|---|---|
| HR | p | HR | p | |
| Age | 1.10 (1.09-1.11) | <0.01 | 1.09 (1.07-1.10) | <0.01 |
| Gender | ||||
| Male | 1 | / | 1 | / |
| Female | 0.68 (0.58-0.80) | <0.01 | 0.56 (0.47-0.66) | <0.01 |
| Race | ||||
| Mexican American | 1 | / | 1 | / |
| Non-Hispanic White | 3.28 (2.12-5.08) | <0.01 | 1.86 (1.27-2.72) | <0.01 |
| Non-Hispanic Black | 2.61 (1.70-4.00) | <0.01 | 1.72 (1.21-2.45) | <0.01 |
| Other | 1.29 (0.84-1.99) | 0.24 | 1.07 (0.71-1.62) | 0.74 |
| Education status | ||||
| Under high school | 1 | / | 1 | / |
| High school or equivalent | 0.57 (0.44-0.74) | <0.01 | 0.76 (0.59-0.98) | 0.03 |
| Above high school | 0.41 (0.32-0.52) | <0.01 | 0.80 (0.60-1.06) | 0.11 |
| Poverty rartio | ||||
| ≤1 | 1 | / | 1 | / |
| 1<to ≤ 3 | 1.54 (1.15-2.06) | <0.01 | 0.89 (0.69-1.14) | 0.35 |
| >3 | 0.73 (0.56-0.94) | 0.02 | 0.59 (0.44-0.77) | <0.01 |
| TSH | ||||
| 0.34<to<5.6 | 1 | / | 1 | / |
| ≤0.34 | 2.34 (1.47-3.73) | <0.01 | 1.52 (0.96-2.41) | 0.07 |
| ≥5.6 | 1.66 (1.04-2.66) | 0.04 | 1.12 (0.64-1.94) | 0.69 |
| Smoking | ||||
| Never | 1 | / | 1 | / |
| Ever | 2.55 (2.00-3.26) | <0.01 | 1.16 (0.91-1.47) | 0.23 |
| Current | 1.62 (1.21-2.15) | <0.01 | 2.03 (1.58-2.61) | <0.01 |
| BMI | ||||
| 18.5≤BMI<25 | 1 | / | 1 | / |
| BMI<18.5 | 2.59 (1.56-4.32) | <0.01 | 2.60 (1.46-4.64) | <0.01 |
| BMI≥25 | 1.04 (0.82-1.31) | 0.74 | 0.82 (0.63-1.07) | 0.14 |
| Diabetes | 3.04 (2.53-3.66) | <0.01 | 1.33 (1.06-1.66) | 0.01 |
| Hypertension | 3.69 (2.99-4.54) | <0.01 | 1.23 (0.98-1.53) | 0.07 |
| Cardiovascular disease | 6.64 (5.28-8.37) | <0.01 | 1.76 (1.42-2.18) | <0.01 |
| Chronic lung disease | 1.51 (1.21-1.89) | <0.01 | 1.25 (1.02-1.54) | 0.03 |
| Arthritis | 3.61 (2.97-4.40) | <0.01 | 1.22 (1.03-1.44) | 0.02 |
| Cancer | 3.37 (2.72-4.17) | <0.01 | 1.03 (0.81-1.32) | 0.80 |
| eGFR<60 | 6.64 (5.39-8.16) | <0.01 | 1.20 (0.97-1.48) | 0.09 |
| TGAb | 1.75 (1.29-2.38) | <0.01 | 1.42 (0.96-2.10) | 0.08 |
| TPOAb | 1.09 (0.86-1.39) | 0.73 | 0.79 (0.59-1.04) | 0.09 |
*Multivariate analysis adjusted for age, sex, race, poverty index, education, smoking, BMI, diabetes, hypertension, CVD, chronic lung disease, arthritis, cancer, TSH, eGFR, TgAb and TPOAb.