Table 3.
Cox regression analysis of factors associated with pharmacological treatment discontinuation in forensic psychiatric patients in Sweden after discharge from forensic psychiatric care (n =856).
| Antipsychotics HR [95% CI] |
p | Antidepressants HR [95% CI] |
p | Psychostimulants HR [95% CI] |
p | Drugs used in addictive disorders HR [95% CI] |
p | Antiepileptics HR [95% CI] |
p | Any psychotropic drug HR [95% CI] |
p | Drugs used for respiratory organs HR [95% CI] |
p | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Being male (female ref.) | 0.94 [0.72–1.23] | 0.64 | 0.85 [0.60–1.20] | 0.35 | 1.36 [0.64–2.89] | 0.43 | 1.25 [0.64–2.47] | 0.51 | 1.58 [0.85–2.94] | 0.15 | 0.96 [0.77–1.19] | 0.71 | 0.91 [0.66–1.27] | 0.58 |
| Age at discharge | 1.01 [1.00–1.01] | 0.21 | 0.99 [0.98–1.00] | 0.03 | 0.97 [0.94–1.01] | 0.11 | 1.01 [0.98–1.03] | 0.57 | 0.99 [0.97–1.01] | 0.31 | 1.00 [0.99–1.01] | 0.76 | 1.00 [0.99–1.01] | 0.89 |
| Length of stay (years) | 0.95 [0.92–0.98] | 0.00 | 0.91 [0.86–0.96] | 0.00 | 0.98 [0.91–1.04] | 0.47 | 0.97 [0.92–1.03] | 0.37 | 0.88 [0.81–0.95] | 0.00 | 0.95 [0.93–0.97] | 0.00 | 0.97 [0.94-1.00] | 0.07 |
| Pre-index crime substance abuse | 1.01 [0.82–1.25] | 0.90 | 1.15 [0.83–1.59] | 0.39 | 1.95 [0.92–4.14] | 0.08 | 1.21 [0.52–2.81] | 0.65 | 1.17 [0.73–1.89] | 0.51 | 1.17 [0.98–1.40] | 0.08 | 0.88 [0.65–1.19] | 0.39 |
| Pre-index crime psychiatric care | 0.74 [0.51–1.07] | 0.11 | 0.48 [0.27–0.86] | 0.01 | 0.24 [0.02–2.36] | 0.22 | 2.02 [0.24–16.95] | 0.52 | 0.95 [0.29–3.15] | 0.93 | 0.84 [0.60–1.16] | 0.29 | 0.33 [0.15–0.69] | 0.00 |
| Psychosis/PD | 0.01 | 0.42 | 0.62 | 0.62 | 0.02 | 0.39 | 0.04 | |||||||
| Psychosis, no PD | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | ||||||||
| PD, no psychosis | 1.10 [0.73–1.64] | 0.65 | 1.32 [0.87–1.99] | 0.20 | 0.60 [0.28–1.29] | 0.19 | 1.29 [0.63–2.64] | 0.49 | 0.95 [0.44–2.08] | 0.90 | 1.19 [0.90–1.58] | 0.21 | 0.93 [0.62–1.38] | 0.71 |
| PD and psychosis | 1.52 [1.03–2.24] | 0.04 | 1.44 [0.75–2.74] | 0.27 | 1.05 [0.13–8.46] | 0.96 | 1.76 [0.39–8.04] | 0.47 | 2.82 [1.33–5.96] | 0.01 | 1.28 [0.90–1.82] | 0.16 | 2.16 [1.23–3.80] | 0.01 |
| Neither psychosis nor PD | 0.74 [0.56–0.98] | 0.03 | 0.99 [0.69–1.42] | 0.95 | 0.77 [0.40–1.47] | 0.43 | 0.84 [0.49–1.45] | 0.53 | 1.57 [0.92–2.68] | 0.09 | 1.03 [0.84–1.27] | 0.76 | 1.02 [0.70–1.49] | 0.90 |
| Having a trustee | 0.52 [0.39–0.70] | 0.00 | 0.65 [0.43–0.98] | 0.04 | 0.35 [0.13–0.91] | 0.03 | Excl. | Excl0. | Excl. | Excl0. | 0.62 [0.49–0.80] | 0.00 | Excl. | Excl0. |
| Having a limited guardian | 0.64 [0.47–0.87] | 0.00 | Excl. | Excl0. | Excl. | Excl0. | Excl. | Excl0. | Excl. | Excl0. | 0.76 [0.60–0.97] | 0.03 | Excl. | Excl0. |
| Supported living accommodation | 0.68 [0.54–0.86] | 0.00 | 0.65 [0.43–0.98] | 0.00 | Excl. | Excl0. | Excl. | Excl0. | 0.51 [0.31–0.82] | 0.01 | 0.73 [0.60–0.88] | 0.00 | 0.64 [0.48–0.87] | 0.00 |
| −2 Log likelihood | 4,415.65 | 0.00 | 1,773.18 | 0.00 | 396.83 | 0.19 | 546.60 | 0.88 | 714.94 | 0.00 | 6,570.57 | 0.00 | 1,961.48 | 0.00 |
| N | 710 | 351 | 79 | 89 | 217 | 829 | 268 |
Due to the forward conditional selection of included, variables that did not contribute to the final model were excluded.