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. 2024 Feb 9;15:1277592. doi: 10.3389/fphys.2024.1277592

TABLE 1.

Demographic, selected preoperative clinical and blood pressure dynamical characteristics of study groups.

Variable All Short ICU LOS Long ICU LOS p value
N = 378 N = 198 N = 180
Age (yrs) 67 [59–75] 65 [57–72] 69 [61–77] < 0.001
Sex: Male 271 (72%) 152 (77%) 119 (66%) 0.022
Body Mass Index (kg/m2) 28.3 [25.4–32.0] 28.7 [25.6–32.0] 28.2 [25.3–32.5] 0.574
Hematocrit (%) 39.3 [35.7–42.3] 40.1 [ 36.0–42.6] 38.2 [35.2–41.7] 0.013
Creatinine Clearance MDRD (ml/min/1.73 m2) 72.6 [58.2–85.5] 75.5 [61.6–90.4] 68.3 [52.7–82.5] < 0.001
Albumin (g/dL) 4.1 [3.8–4.5] 4.2 [3.9–4.5] 4.1 [3.8–4.4] 0.005
EuroSCORE II (%) 1.95 [1.15–4.38] 1.69 [1.01–2.96] 2.82 [1.41–5.67] < 0.001
STS Morbidity/Mortality (%)* 12.0 [7.9–20.1] 11.0 [7.0–16.4] 14.5 [9.0–25.0] < 0.001
Surgery type 0.118
 CABG 196 (52%) 109 (55%) 87 (48%)
 CABG + Valve 65 (17%) 26 (13%) 39 (22%)
 Valve 79 (21%) 45 (23%) 34 (19%)
 Other 38 (10%) 18 (9%) 20 (11%)
NYHA 0.974
 I 43 (11%) 23 (12%) 20 (11%)
 II 168 (44%) 88 (44%) 80 (44%)
 III 112 (30%) 57 (29%) 55 (31%)
 IV 55 (15%) 30 (15%) 25 (14%)
BPF (%) 62.4 [56.2–67.8] 60.6 [54.4–65.9] 64.2 [57.5–70.6] < 0.001
Mean SBP (mmHg) 136 [122–152] 135 [122–151] 138 [122–153] 0.541
SD (mmHg) 7.24 [5.85–9.26] 7.16 [5.85–9.02] 7.34 [5.85–9.43] 0.909
CV 0.053 [0.043–0.066] 0.053 [0.043–0.066] 0.054 [0.042–0.065] 0.703
ARV (mmHg) 2.97 [2.25–3.86] 2.94 [2.21–3.76] 2.99 [2.26–4.08] 0.264
DFA ⍺1 1.11 [0.92–1.27] 1.14 [0.96–1.31] 1.07 [0.86–1.25] 0.009

The values for continuous variables are the median and [inter-quartile range]. Values for binary variables are number of participants and (their percentage) in the population/sub-populations. Statistically significant p value are highlighted in bold. Abbreviations: ARV, average real variability; BPF, blood pressure fragmentation; CABG, coronary artery bypass graft; CV, coefficient of variation; DFA, detrended fluctuation analysis; EuroSCORE, European System for Cardiac Operative Risk Evaluation; ICU, intensive care unit; LOS, length of stay; MDRD, modification of diet in renal disease equation; NYHA, New York Heart Association; SBP, systolic blood pressure; SD, standard deviation; and STS, Society of Thoracic Surgeons.

*The STS Morbidity/Mortality risk score was calculated for all patients who qualified.