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. 2024 Feb 9;15:1277592. doi: 10.3389/fphys.2024.1277592

TABLE 5.

Unadjusted and adjusted modified Poisson regression analyses of the associations between each preoperative SBP dynamical metric and long ICU LOS (>40 h).

A. Sub-group with STS Risk Score (N = 340)
Model 0: Unadjusted Model 1: Age and Sex Model 2: STS
Variable RR 95% CI p value RR 95% CI p value RR 95% CI p value
BPF (%) 1.26 1.13 1.40 < 0.001 1.18 1.05 1.32 0.006 1.16 1.03 1.30 0.012
Mean SBP (mmHg) 1.01 0.91 1.13 0.833 0.99 0.88 1.10 0.805 1.02 0.93 1.13 0.640
SD (mmHg) 0.95 0.84 1.06 0.362 0.95 0.85 1.07 0.410 0.98 0.87 1.10 0.696
CV 0.93 0.83 1.05 0.225 0.95 0.84 1.06 0.341 0.95 0.85 1.06 0.380
ARV (mmHg) 1.11 1.01 1.22 0.035 1.06 0.97 1.17 0.196 1.06 0.97 1.16 0.220
DFA ⍺1 0.88 0.79 0.98 0.021 0.95 0.85 1.07 0.377 1.00 0.88 1.12 0.941
STS (%) 1.30 1.17 1.44 < 0.001
B. Group with EuroSCORE II (N = 378)
Model 0: Unadjusted Model 1: Age and Sex Model 2: EuroSCORE II
Variable RR 95% CI p value RR 95% CI p value RR 95% CI p value
BPF (%) 1.24 1.13 1.37 < 0.001 1.18 1.06 1.32 0.003 1.15 1.03 1.28 0.010
Mean SBP (mmHg) 1.03 0.93 1.15 0.569 1.01 0.91 1.12 0.817 1.04 0.94 1.15 0.406
SD (mmHg) 0.96 0.86 1.07 0.470 0.96 0.87 1.07 0.497 0.98 0.88 1.09 0.654
CV 0.94 0.84 1.05 0.252 0.95 0.85 1.05 0.320 0.95 0.85 1.05 0.306
ARV (mmHg) 1.11 1.02 1.21 0.018 1.08 0.99 1.18 0.086 1.06 0.97 1.16 0.195
DFA ⍺1 0.86 0.78 0.95 0.004 0.91 0.82 1.01 0.079 0.97 0.87 1.08 0.565
EuroSCORE II (%) 1.30 1.19 1.42 < 0.001

Values presented are the relative risk and 95% CI, for standardized variables. Separate models were fitted for each of the different BPV, indicators. The adjustments were age and sex in Model 1, and STS, or EuroSCORE II, in Model 2. Statistically significant p values are highlighted in bold. Abbreviations: ARV, average real variability; BPF, blood pressure fragmentation; CI, confidence interval; CV, coefficient of variation; DFA, detrended fluctuation analysis; EuroSCORE, European System for Cardiac Operative Risk Evaluation; ICU, intensive care unit; LOS, length of stay; RR, relative risk; SD, standard deviation; SBP, systolic blood pressure; SD, standard deviation; STS, Society of Thoracic Surgeons.