| ADP | adenosine diphosphate |
| AMPK | adenosine monophosphate protein kinase |
| APAF-1 | apoptotic protease activating factor 1 |
| ATP | adenosine triphosphate |
| BAX | Bcl2-associated X protein |
| BNIP3 | Bcl-2-interacting protein 3 |
| Ca2+ | calcium |
| Clec16a | C-type lectin domain containing 16a |
| cGAS-STING | cyclic GMP-AMP synthase - stimulator of interferon genes |
| DIMT1 | dimethyladenosine transferase 1 |
| DRP-1 | dynamin-related protein 1 |
| ER | endoplasmic reticulum |
| ETC | electron transport chain |
| FFA | free fatty acids |
| GCK/HKIV | glucokinase/hexokinase IV |
| GDH | glutamate dehydrogenase |
| GLUT1/2/3 | glucose transporters 1/2/3 |
| GSIS | glucose-stimulated insulin secretion |
| GTP | guanosine triphosphate |
| HFD | high fat diet |
| HIF-1α | hypoxia-inducible factor 1-α |
| ICD | isocitrate dehydrogenase |
| IFNγ | interferon gamma |
| IGF-1 | insulin growth factor 1 |
| IL-1⍺/β | interleukin 1 alpha/beta |
| IL6 | interleukin 6 |
| MCU | mitochondrial calcium uniporter |
| MELAS | mitochondrial encephalopathy associated with lactic acidosis and stroke-like episodes |
| MFN1/2 | mitofusin 1/2 |
| MICU1/2 | mitochondrial calcium uptake 1/2 |
| MIDD | maternally inherited diabetes and deafness |
| MIRO1 | mitochondrial Rho protein 1 |
| MMP | mitochondrial membrane potential |
| MPC1/2 | mitochondrial pyruvate carriers 1/2 |
| MOTS-c | mitochondrial open reading frame of the 12S rRNA type-c |
| MRPs | mitoribosomal proteins |
| mtDAMPs | mitochondrial damage-associated molecular patterns |
| mt-ND2 | mitochondrial gene NADH dehydrogenase 2 |
| mTOR | mammalian target of rapamycin |
| mtROS | mitochondrial reactive oxygen species |
| NAD/H | nicotinamide dinucleotide/reduced |
| NFκB | nuclear factor kappa-light-chain-enhancer of activated B cells |
| NOD SCID | nonobese diabetic severe combined immunodeficiency |
| OPA-1 | optic atrophy 1 |
| OXPHOS | oxidative phosphorylation |
| PAK1 | p21 activated kinase 1 |
| PC | pyruvate carboxylase |
| PDH | pyruvate dehydrogenase |
| PD-L1 | programmed cell death ligand 1 |
| PEP | phosphoenolpyruvate |
| PINK1 | PTEN-induced putative kinase 1 |
| PK | pyruvate kinase |
| PM | plasma membrane |
| PPP | pentose phosphate pathway |
| ROS | reactive oxygen species |
| SASP | senescence-associated secretory phenotype |
| SC | stem cell |
| SDH | succinate dehydrogenase |
| SENP1 | sentrin/SUMO-specific protease 1 |
| SERCA | sarco/endoplasmic reticulum calcium ATPase |
| T1D | type 1 diabetes |
| T2D | type 2 diabetes |
| TCA | tricarboxylic acid cycle/citric acid cycle |
| TCR | T cell receptor |
| TFB1M | mitochondrial transcription factor B1 |
| TFB2M | mitochondrial transcription factor B2 |
| TFEB | transcription factor EB |
| TNF | tumor necrosis factor |
| UCP2 | uncoupling protein 2 |
| UPR | unfolded protein response |
| VGCC | voltage gated calcium channel |