Table 1.
Health statea | Follow-up proceduresb | Number of days of uncertainty about cancer diagnosisc |
---|---|---|
A. Cancer screening with negative result | ||
B1. False positive for lung cancer without head or neck involvement | CT scan | 10 |
B2. False positive for lung cancer with possible head or neck involvement | CT scan; PET-CT | 25 |
B3. False positive for lung cancer with a 6-month follow-up scan | CT scan | 185 |
C. False positive for colorectal cancer | Colonoscopy | 14 |
D1. False positive for breast cancer; no biopsy or MRI | Mammogram/ultrasound (at same visit) | 10 |
D2. False positive for breast cancer; biopsy performed | Mammogram/ultrasound/biopsy (at same visit) | 10 |
D3. False positive for breast cancer; MRI performed | Mammogram/ultrasound (at same visit); MRI | 20 |
E1. False positive for pancreatic cancer; follow-up CT scan | CT scan | 9 |
E2. False positive for pancreatic cancer; follow-up CT scan and PET-CT | CT scan; PET-CT | 23 |
CT computed tomography, MRI magnetic resonance imaging, PET-CT positron emission tomography scan and computed tomography scan
aThe ‘D health states’ describing false positives for breast cancer were not presented to the male participants. Therefore, men only valued seven health states, whereas women valued all 10 health states
bEach health state described the typical follow-up procedures that would occur after a false-positive screening result. For some of the health states (e.g., B1, E1), a single follow-up procedure was necessary to confirm that the original result was a false positive. For other health states (e.g., B2, E2), multiple follow-up tests were required
cEach health state included a timeline illustrating the number of days between the false-positive screening result and the eventual resolution when the result is confirmed to be a false positive. This is the period of uncertainty during which the hypothetical patient does not know whether the positive screening result was accurate