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. 2024 Feb;17(1):111–123. doi: 10.1016/j.mucimm.2023.11.005

Fig. 5.

Fig. 5

Gut cytokine profile following recent SARS-CoV-2 infection associates with systemic anti-SARS-CoV-2 antibody induction. (A) Correlation between faecal cytokines measured from day 7 samples (n = 45) and day 28 serum DABA levels, peak SASS, peak GISS, URT viral load at day 7, faecal viral load at day 7, and log 10 of peak viral load in the URT. Correlation measured by Kendall rank correlation coefficient, tau. Correlations that are statistically different than zero (p < 0.05) are marked with an asterisk (*). (B) Individual correlation graphs between cytokines that significantly correlate with D28 DABA measurements. (C) Correlation matrix of faecal cytokines measured from PCR+ day 7 samples (n = 45). Correlation of cytokines against D28 serum DABA measurements are shown along the top and left axes. Correlation measured by Kendall rank correlation coefficient, tau. Correlations that are statistically different than zero (p < 0.05) are marked with an asterisk (*). (D) A receiver operating characteristic (ROC) graph showing the sensitivity and specificity with which the antibody-associated cytokine profile score predicted the need for invasive ventilation in the ISARIC4C cohort (n = 43).