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. 2024 Jan 18;8(1):102315. doi: 10.1016/j.rpth.2024.102315

Table 4.

Results of univariate regression analysis.

Independent variable Favorable outcomes Spin present Discrepancy between protocol and reported outcomes Retrospective registration
Commercial sponsorship (SE) -0.095 (0.60)a 0.33 (0.7379)a -1.47 (0.86)a -0.49 (1.03)a
 OR (95% CI) 0.91 (0.28, 3.02) 1.39 (0.32, 6.00) 0.23 (0.04, 1.18) 0.62 (0.08, 5.63)
Composite outcome (SE) 0.49 (0.67)a 0.71 (0.75)a 1.45 (0.92)a 1.50 (0.97)a
 OR (95% CI) 2.02 (0.45, 9.12) 2.02 (0.45, 9.12) 4.27 (0.72, 28.91) 4.50 (0.73, 37.66)
Sample size (SE) 0.00062 (0.00060)a -0.0018 (0.0013)a -0.00022 (0.00061)a -0.00045 (0.00074)a
 OR (95% CI) 1.00 (1.00, 1.00) 1.00 (1.00, 1.00) 1.00 (1.00, 1.00) 1.00 (1.00, 1.00)
LTFU (SE) -0.030 (0.040)a 0.085 (0.090)a -20.93 (15091.4)a 0.0028 (0.035)a
 OR (95% CI) 0.97 (0.88, 1.04) 1.09 (0.98, 1.41) 0 (0, ∞) 1.00 (0.92, 1.08)
Year of publication (SE) 0.078 (0.048)a -0.050 (0.052)a 0.032 (0.082)a -0.079 (0.099)a
 OR (95% CI) 1.08 (0.99, 1.20) 0.95 (0.85, 1.05) 1.03 (0.87, 1.22) 0.92 (0.76, 1.12)
Multicenter trial (SE) -0.98 (0.62)a -0.81 (0.89)a -0.22 (0.96)a -0.69 (0.83)a
 OR (95% CI) 0.38 (0.11, 1.16) 0.44 (0.06, 2.27) 0.80 (0.10, 4.85) 0.50 (0.09, 2.61)
Duration of follow-up (SE) 0.00016 (0.00044)a -0.00035(0.0019)a 0.0014 (0.0020)a 0.00065 (0.00068)a
 OR (95% CI) 1.00 (1.00, 1.00) 1.00 (1.00, 1.00) 1.00 (1.00, 1.01) 1.00 (1.00, 1.00)
Primary LMWH (SE) 0.37 (1.2)a 1.15 (1.49)a 0.22 (1.31)a 0.24 (1.32)a
 OR (95% CI) 1.44 (0.16, 30.81) 3.17 (0.11, 88.86) 1.25 (0.05, 15.66) 1.27 (0.10, 30.47)
Use of ITT (SE) -0.33 (0.59)a 1.07 (0.75)a -1.57 (0.93)a 0.14 (0.74)a
 OR (95% CI) 0.72 (0.22, 2.32) 2.91 (0.67, 13.49) 0.21 (0.03, 1.13) 1.15 (0.27, 5.07)

ITT, intention-to-treat; LMWH, low-molecular-weight heparin; LTFU, loss to follow-up; OR, odds ratio.

a

Nonsignificant P > .05.