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PDP1 activity is required for TLCL-mediated rescue of PDH activity.A, phosphorylated PDH (p-PDH) levels and PDH activity (B) were evaluated in mitochondria from TAZ-KO myoblasts treated with or without phosphatase inhibitor and supplemented for 2.5 h with or without C(18:2)4 CL. Data points represent mean ±S.D. (error bars) for each individual biological replicate of each group. ∗ 0.01<p < 0.05, ∗∗ 0.001<p < 0.01.
