Table 3.

Non-neurologic features.

patient	telangiectasias	short stature	BMI (Z-score)	endocrine disease	respiratory symtoms	malignancy	age at first cancer, y	other diagnoses
p1family1	yes	no	16 (+0.5)	no	non-allergic asthma	no		vitiligo, laryngomalacia
p2family1	yes	no	17 (0)	no	persistent cough	no		laryngomalacia
p3family2	yes	yes	15	no	no	no		scoliosis, constipation
p4family2	no	yes	21	hypothyroidism, diabetes type 2	no	no		hepatic steatosis, primary biliary cholangitis
p5family3	yes	yes	27 (+1.5)	no	noa	no		no
p6family3	yes	yes	29	no	no	no		constipation
P7family3	no	yes	18 (−2)	no	no	no		constipation
P8family4	yes	no	13 (−2.5)	no	mild respiratory failure	DLBCL	7	immune thrombocytopenic purpura
p9family5	yes	yes	23	no	no	no		dysautonomia, Tietze syndrome
p10family6	yes	no	26	diabetes type 2	asthma	no		vitiligo, essential hypertension
p11family7	yes	no	25	hyperthyroidism	restrictive lung diseasea	thyroid, vulva, anal cancer	41	no
p12family8	yes	no	23	no	no	colon cancer	49	no
p13family9	yes	NA	NA	no	no	no		no
p14family10	yes	no	21	hypothyroidsim, prolactinoma	asthma, suspected restrictive lung diseasea	pancreas cancer	47	no

^aBody mass index (BMI) is the most recent recorded for each patient. Z-scores are proved for pediatric patients. DLBCL, Diffuse large B cell lymphoma.