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. Author manuscript; available in PMC: 2024 Feb 23.
Published in final edited form as: Exp Neurol. 2019 Nov 18;325:113119. doi: 10.1016/j.expneurol.2019.113119

Fig. 9. CHI does not alter the number of GFP+ oligodendrocyte progenitors in the cerebral cortex.

Fig. 9.

The lineage adoption of injury-induced Notch1CR2-GFP+ cells in the cerebral cortex was determined by immunostaining in a mouse model of closed head injury (CHI). Confocal images show GFP+ cells expressing oligodendrocyte progenitor marker NG2 in coronal sections of the cerebral cortex at 14 DPI. Arrowheads indicate co-labeled cells. Dash line boxed region shows an example of NG2+/GFP+ cells in separate image channels and in a higher magnification with orthogonal views of Z-stack. Quantification shows no significant (NS) increase in the number of NG2+/GFP+ (0.17 ± 0.04% in CHI vs. 0.03 ± 0.02% in sham; NS) oligodendrocyte progenitors out of all the cells in the cerebral cortex of injured animals compared to sham animals. Scale bar = 20 μm, Mean ± SEM, n = 6.