Table 3:
HLA-A*32:01 Allele and Carrier Frequency
| Population | No. | AF | CF | p value |
|---|---|---|---|---|
| Vancomycin (High Confidence) | 9 | 0.444 | 78% | ref |
| Vancomycin (Possible & Unlikely) | 81 | 0.006 | 1.2% | <0.001 |
| All other Drug-induced liver injury | 1708 | 0.034 | 6.6% | <0.001 |
| Caucasian (European) * | 1,242,090 | 0.035 | ~6.8% | <0.001 |
| African Americans * | 416,581 | 0.015 | ~2.5% | <0.001 |
| Asian Americans (Chinese) * | 99,672 | 0.006 | ~1% | <0.001 |
| Hispanic (Mexican-Americans) * | 261,235 | 0.027 | ~5% | <0.001 |
data from www.alleleFrequencies.net, assessed 12.06.2021
Abbreviations: AF, allele frequency; CF, carrier frequency