Table 4.

Performance of the R-score, C-model, and CR-model in predicting post-operative outcomes

Outcome	Model	Development set	P value	Test set	P value
		C-index (95% CI)	C vs. CR model	C-index (95% CI)	C vs. CR model
Recurrence-free survival
	R-score	0.778 (0.748–0.808)		0.716 (0.659–0.772)
	C-model	0.761 (0.732–0.790)		0.662 (0.591–0.733)
	CR-model	0.811 (0.780–0.842)	0.045	0.734 (0.674–0.793)	0.012
Overall survival
	R-score	0.648 (0.588–0.709)		0.674 (0.597–0.751)
	C-model	0.697 (0.638–0.755)		0.675 (0.605–0.745)
	CR-model	0.730 (0.673–0.787)	0.127	0.781 (0.721–0.841)	0.043

C-index, concordance index; CI, confidence interval; C-model, clinical model; CR-model, clinical-radiomics model; R-score, radiomics score