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. Author manuscript; available in PMC: 2024 Feb 23.
Published in final edited form as: J Mol Biol. 2023 Dec 20;436(4):168409. doi: 10.1016/j.jmb.2023.168409

Table 1.

Binding parameters for PQBP1 peptides and disulfide-stabilized HIV-1 CA hexamer

PQBP1 peptide Apparent Kd (nM) Hill coefficient CA sp. activity
Nt 503 ± 66 1.6 ± 0.1 0.8
15–5 85.0 ± 1.0 1.8 ± 0.4 0.8
15–6 54.0 ± 0.4 3.0 ± 0.2 0.8

Note: Kd and Hill coefficient were treated as floating parameters during fitting, but not CA specific activity. Values are presented as mean ± S.D. of four (Nt) or three (15–5 and 15–6) independent determinations.