PPID keynotes Minimal epidemiological data available; Pathogenesis assumed to be like in horses; Beware of hypertrichosis and calm behavior; Resting ACTH in healthy donkeys is higher than in horses; Caution with seasonally adjusted ACTH ranges; TRH-stimulation test recommended for diagnosis; Pergolide dosing like in horses; Measure ACTH at 2–3 months and then 6–12 months.