| 1. | exp bile duct/ |
| 2. | biliary tra*.mp. |
| 3. | bile duct*.mp. |
| 4. | cholang*.mp. |
| 5. | 1 or 2 or 3 or 4 |
| 6. | exp malignant neoplasm/ |
| 7. | (cancer* or tum?r or carcinoma* or adenocarcinoma* or cholangiocarcinoma*).mp. |
| 8. | malignan*.mp. |
| 9. | 6 or 7 or 8 |
| 10. | surgery/or surgery.mp. or cancer surgery/ |
| 11. | resect*.mp. |
| 12. | hepatectomy.mp. or liver resection/ |
| 13. | (pancreaticoduodenectomy or pancreatoduodenectomy).mp. or pancreaticoduodenectomy/ |
| 14. | (whipple* or hepatopancreaticoduodenectomy* or hepatopancreatoduodenectomy).mp. |
| 15. | 10 or 11 or 12 or 13 or 14 |
| 16. | biomarker*.mp. or biological marker/ |
| 17. | (blood test* or plasma* or serum*).mp. |
| 18. | urin*.mp. |
| 19. | urine sampling/ |
| 20. | immunohistochemistry/or immunohistoch*.mp. |
| 21. | protein expression/or immunofluorescence/or immunofluoresc*.mp. |
| 22. | 16 or 17 or 18 or 19 or 20 or 21 |
| 23. | recurren*.mp. |
| 24. | recurrent disease/ |
| 25. | exp survival/ |
| 26. | surviv*.mp. |
| 27. | prognosis/or cancer prognosis/or prognos*.mp. |
| 28. | 23 or 24 or 25 or 26 or 27 |
| 29. | 5 and 9 and 15 and 22 and 28 |