Table 1.
Demographics and clinical characteristics of patients.
| Variables | Total (n = 4039) | NLR ≤ 12 (n = 2513) | NLR > 12 (n = 1526) | p, OR (95% CI) |
|---|---|---|---|---|
| Age, median (IQR) | 78 (65, 88) | 77 (65, 88) | 80 (67, 88) | 0.003 |
| Sex, Male, no. (%) | 2172 (53.8%) | 1293 (51.5%) | 879 (57.6%) | <0.001, 1.28 (1.13, 1.46) |
| Race, no. (%) | 0.038 | |||
| White | 3805 (94.2%) | 2349 (93.5%) | 1456 (95.4%) | |
| Asian | 42 (1.0%) | 31 (1.2%) | 11 (0.7%) | |
| African American | 64 (1.6%) | 50 (2.0%) | 14 (0.9%) | |
| Others | 128 (3.2%) | 83 (3.3%) | 45 (2.9%) | |
| Ethnicity, no. (%) | 0.401 | |||
| Non-Hispanic | 3897 (96.5%) | 2423 (96.4%) | 1474 (96.6%) | |
| Hispanic | 65 (1.6%) | 45 (1.8%) | 20 (1.3%) | |
| Unknown/Other | 77 (1.9%) | 45 (1.8%) | 32 (2.1%) | |
| Comorbidities, no. (%) | ||||
| Congestive heart failure | 1118 (27.7%) | 703 (28.0%) | 415 (27.2%) | 0.592, 0.96 (0.83, 1.11) |
| COPD | 1310 (32.4%) | 740 (29.4%) | 570 (37.4%) | <0.001, 1.43 (1.25, 1.63) |
| Diabetes | 1220 (30.2%) | 790 (31.4%) | 430 (28.2%) | 0.029, 0.86 (0.74, 0.98) |
| Chronic kidney disease | 1159 (28.7%) | 724 (28.8%) | 435 (28.5%) | 0.836, 0.99 (0.86, 1.13) |
| Malignancy | 938 (23.5%) | 576 (22.9%) | 372 (24.4%) | 0.290, 1.08 (0.93, 1.26) |
| Neutrophil/lymphocyte ratio, median, (IQR) | 9.26 (5.13, 16.35) | 6.09 (3.80, 8.67) | 19.71 (14.86, 27.88) | |
| Clinical Severity Scores | ||||
| Pneumonia Severity Index, median (IQR) | 113 (87, 141) | 109 (83, 136) | 119 (93, 148) | <0.001 |
| CURB 65 | 3 (2, 3) | 3 (2, 3) | 3 (2, 4) | <0.001 |
| APACHE III | 65 (52, 80) | 64 (51, 79) | 66 (53, 81) | 0.013 |
| Need for vasopressor during hospitalization, no. (%) | 888 (22.0%) | 512 (20.4%) | 376 (24.6%) | 0.002, 1.28 (1.10, 1.49) |
APACHE: Acute Physiology and Chronic Health Evaluation, CI: confidence interval, COPD: Chronic Obstructive Pulmonary Disease, NLR: neutrophil/lymphocyte ratio, IQR: interquartile range, OR: odds ratio.