ABC transporters |
ATP-binding cassette transporters |
ATM |
Ataxia Telangiectasia Mutated |
BBB |
Blood–brain barrier |
BCL-XL |
B-cell lymphoma-extra large |
CAF |
Cancer-associated fibroblast |
CAR-T |
Chimeric antigen receptor T-cell therapy |
CAT |
Catalase |
CDH2 |
Cadherin 2 |
cGAS |
Cyclic GMP-AMP synthase |
Chk2 |
Checkpoint kinase 2 |
CPT |
Camptothecin |
CRPC |
Castration-resistant prostate cancer |
CSC |
Cancer stem cell |
DOX |
Doxorubicin |
DSB |
Double-strand break |
dsDNA |
Double-stranded DNA |
ECM |
Extracellular matrix |
EV |
Extracellular Vesicles |
GSH |
Glutathione |
HDAC |
Histone deacetylase |
HGF |
Hepatocyte growth factor |
HR |
Homologous recombination |
ICIT |
Immune checkpoint inhibitor therapies |
MCH-I |
Major histocompatibility class I |
MDR1 |
Multi-Drug Resistance Protein 1 |
miRNA |
microRNA |
MMDX |
Nemorubicin |
MXT |
Mitoxantrone |
NADPH |
Nicotinamide adenine dinucleotide phosphate |
NGS |
Next-generation sequencing |
NHEJ |
Non-homologous end joining |
PARP |
Poly(ADP-ribose) polymerase |
PD-1/PD-L1 [PD-(L)1] |
Programmed cell death protein 1/Programmed death-ligand 1 |
PEG |
Polyethylene glycol |
ROS |
Reactive oxygen species |
RPA |
Replication Protein A |
SNP |
Single nucleotide polymorphism |
SOD |
Superoxide dismutase |
ssDNA |
Single-stranded DNA |
TGF |
Tumor growth factor |
TGF-β |
Transforming growth factor beta |
TME |
Tumor microenvironment |
TNBC |
Triple-negative breast cancer |
TOP1cc |
Topoisomerase I cleavage complex |
TOP3α |
Topoisomerase III alpha |
TOP3β |
Topoisomerase III beta |
TOPI |
DNA topoisomerase I |
TOPII |
DNA topoisomerase II |
TOPmt |
Mitochondrial DNA topoisomerase |
VP-16 |
Etoposide |
ZEB1 |
Zinc finger E-box-binding homeobox 1 |