Table 2.

Association of clinical features and ICDs in patients with Parkinson’s disease.

	ICD Patients	Non-ICD Patients	p
Male	71.11%	59.12%	0.1504
Age at examination (years)	65.00 ± 9.15	63.51 ± 9.57	0.3671
Age at onset (years)	53.60 ± 9.98	54.45 ± 11.15	0.6488
Disease duration (years)	11.42 ± 4.76	8.98 ± 6.23	0.0038 *
MDS-UPDRS part III “OFF state”	39.75 ± 16.41	42.44 ± 19.59	0.6548
MDS-UPDRS part III “ON state”	19.45 ±12.40	20.91 ± 13.06	0.6886
Motor fluctuations	82.22%	50.37%	0.0002 *
Depressive disorders:			0.2238
Minimal depression	86.67%	82.48%
Mild depression	6.67%	17.52%
Moderate depression	6.67%	2.92%
Severe depression	0.00%	0.00%
Dementia:			0.7234
No dementia	60.00%	54.74%
MCI	28.89%	35.77%
Mild dementia	8.89%	8.76%
Moderate dementia	0.00%	0.73%
Sleep disorders	66.67%	46.72%	0.0201 *
Dopamine agonist use	84.44%	53.52%	0.0002 *
DA-LEDD	169.76 ± 115.42	115.32 ± 208.04	0.0009 *
MAO-B inhibitors	24.44%	16.79%	0.2529
Amantadine	33.33%	26.28%	0.3605
Levodopa	93.33%	84.67%	0.1604
LD-LEDD	986.11 ± 642.94	723.98 ± 665.06	0.0147 *
Total LEDD	1327.53 ± 727.62	927.46 ± 665.06	0.0018 *

Data are shown as numbers and percentages for qualitative variables and mean ± SD for quantitative variables. *—statistically significant differences; DA—dopamine agonist; LEDD—levodopa equivalent daily dose; LD—levodopa; MDS-UPDRS—MDS Unified Parkinson’s Disease Rating Scale.