Table 1.

Studies analyzing the association between ALS and COVID-19.

Reference	Type of Study	Type of Contact with the Virus	Association between COVID-19 and ALS
Bonetto et al., 2022 [4]	Cohort study	Infection	Associated, due to BBB damage, bioenergetic failure, and autoimmune and innate neuroimmune responses.
Zhang & Zhou, 2022 [2]	Mendelian randomization	Infection	Not associated
Abu-Abaa et al., 2023 [1]	Case report	Infection	Suggested
Feghali et al., 2023 [8]	Case report	Vaccine	Suggested