Table 1.
Patient characteristics.
| Characteristics | Ovarian Cancer | Other Cancer | Borderline Ovarian Tumor | p |
|---|---|---|---|---|
| Number, n | 107 | 14 | 7 | |
| Age, years | 67.2 (56.8–74.0) | 62.6(55.0–70.1) | 55.2 (43.4–58.1) * | 0.019 |
| BMI, kg/m2 | 23.8 (21.1–27.5) | 25.5 (22.4–29.8) | 35.9 (26.6–43.9) * | 0.017 |
| Treatment, n (%) | ||||
| Primary surgery | 49 (58.8) | |||
| Interval surgery | 41 (38.3) | |||
| Chemotherapy | 17 (15.9) | |||
| Postmenopausal, n (%) | ||||
| Yes | 92 (86.0) | 10 (71.4) | 4 (57.1) | 0.050 |
| No | 15 (14.0) | 4 (28.6) | 3 (42.9) | |
| Smoker, n (%) | ||||
| Never | 49 (45.8) | 6 (50.0) | 4 (57.1) | 0.408 |
| Former | 41 (38.3) | 5 (41.7) | 2 (28.6) | |
| Current | 16 (15.0) | 1 (8.3) | 0 (0.0) | |
| Unknown/missing | 1 (0.9) | 0 (0.0) | 1 (14.3) | |
| Clinical stage, n (%) | ||||
| I | 7 (6.5) | 1 (9.1) * | 5 (71.4) * | 0.000 |
| II | 4 (3.7) | 1 (9.1) | 0 (0.0) | |
| III | 64 (59.8) | 4 (36.4) | 1 (14.3) | |
| IV | 32 (29.9) | 2 (18.2) | 0 (0.0) | |
| Unknown/missing | 0 (0.0) | 3 (27.3) | 1 (14.3) | |
| CCI, n (%) | ||||
| 0 | 89 (83.2) | 13 (92.9) | 5 (71.4) | 0.327 |
| 1 | 12 (11.2) | 0 (0.0) | 1 (14.3) | |
| 2 | 3 (2.8) | 1 (7.1) | 1 (14.3) | |
| 3 | 3 (2.8) | 0 (0.0) | 0 (0.0) | |
| Performance score, n (%) | ||||
| 0 | 50 (46.7) | 9 (75) | 3 (42.9) | 0.483 |
| 1 | 34 (31.8) | 2 (16.7) | 4 (57.1) | |
| 2 | 19 (17.8) | 1 (8.3) | 0 (0.0) | |
| 3 | 4 (3.7) | 0 (0.0) | 0 (0.0) | |
| CA125, U/mL | 850 (352–1870) | 425 (112–820) * | 259 (122–560) * | 0.007 |
| RMI score | 5463 (2196–12,150) | 2460 (441–3860) * | 840 (366–5040) * | 0.004 |
| Follow-up, months | 38.4 (18.6–51.3) | 39.7 (14.3–57.2) | 67.6 (59.5–70.5) * | 0.001 |
| Mortality at endpoint, n (%) | 73 (68.2) | 7 (50.0) * | 0 (0.0) * | 0.000 |
Baseline and follow-up characteristics in women with ovarian cancer, other cancer, or borderline tumor. Other cancers included cervix cancer (n = 1), endometrial cancer (n = 5), teratoma (n = 1), neuroendocrine carcinoma (n = 2), and cancer of unknown origin (n = 5). Categorical variables are indicated as number (n) and percentage (%) of patients, and continuous variables are indicated as median (25th percentile; 75th percentile). p-value: comparison of all groups using one-way ANOVA or Kruskal–Wallis test. * p < 0.05 when compared to the ovarian cancer group using Student’s t-test or Wilcoxon rank-sum test. BMI, body mass index; CA125, cancer antigen 125; CCI, Charlson Comorbidity Index; RMI, risk of malignancy index.