Table 2.

The prevalence of H. pylori infection among patients with gastroduodenal perforation.

No.	Study	Topic	Total Number of Patients	H. pylori Prevalence (n)
1	Tokunaga et al. (1998) [8]	Impact of H. pylori in the severity of a perforated ulcer.	113	92% (104)
2	Debongnie et al. (1995) [9]	Recurrence of gastric perforation in patients infected with H. pylori.	36	56% (20)
3	Casali et al. (2012) [10]	H. pylori test in patient with gastric perforation.	14	84.6% (12)
4	Thirupathaiah et al. (2020) [3]	The association between H. pylori and a perforated gastroduodenal ulcer.	48	12.5% (6)
5	Ha et al. (2016) [11]	The gastrointestinal safety of herbal medicine in patients with osteoarthritis.	761	53% (403)
6	Vonkeman et al. (2007) [12]	PPI reduced the risk of NSAID ulcer complications.	104	20% (21)
7	Köninger et al. (2004) [13]	Laparoscopic repair of a perforated gastroduodenal ulcer.	20	65% (13)
8	Agaba et al. (2016) [14]	The incidence of complicated PUD and analyses changes in surgical management.	400	84% (336)
9	Pescatore et al. (1998) [3]	A new method combining laparoscopy and endoluminal endoscopy was designed to ensure complete closure of the perforation.	6	100% (2)
10	Okidi et al. (2020) [17]	An observational study of patients with suspected NTGDP who had exploratory laparotomy during a one-year period.	29	13.8% (4)
11	Yan et al. (2019) [15]	Gastroduodenal perforation in children: causes, symptoms, and customized surgical care.	20	30% (6)
12	Kujath et al. (2002) [16]	Perforated gastroduodenal ulcers: surgical management and prognosis.	102	26.3% (27)