Table 4.

Other risk factors associated with a gastroduodenal event.

No.	Study	Risk	Treatments	Total Number of Patients	Prevalence of Gastroduodenal Perforation (n)
1	Ahonen et al. (1977) [25]	Renal transplantation	Antacids	434	10.3% (45)
2	Stuart et al. (1981) [30]	Renal transplantation	Antacids	167	4.7% (8)
3	Benoit et al. (1993) [23]	Renal transplantation	Immuno-suppressant, steroids	614	16.2% (99)
4	Meyers et al. (1979) [24]	Renal transplantation	Steroids	343	37% (127)
5	Gupte et al. (2010) [34]	Intestinal transplantation	Immunosuppressive regimen and cyto-megalo-virus (CMV) prophylaxis	46	13% (6)
6	Boufi et al. (2013) [28]	Pancreatic duodenectomy	Octreotide	14	7% (1)
7	Chan and Mann (1989) [27]	Neurosurgical	Dexamethasone and cimetidine	381	2.4% (9)
8	Bhatt et al. (2010) [30]	Coronary artery disease	Clopidogrel in combination with either omeprazole or placebo	3761	1.1% (42)
9	Moayyedi et al. (2019) [31]	Cardiovascular and peripheral artery disease	Rivaroxaban, aspirin, and pantoprazole	8791	1.2% (106)
10	Dong et al. (2012) [29]	Cardiovascular operations	Cardiopulmonary bypass	2349	6.1% (144)
11	Geisel et al. (2014) [39]	Biliodigestive anastomosis	Bilobar or unilobar treatment	143	6.29% (9)
12	Pomar et al. (2010) [32]	Hernia surgery	NA	39	20.5% (8)
13	Ogata et al. (1996) [33]	Colorectal cancer	Chemotherapy	43	23% (10)
14	Simons et al. (1995) [38]	Stress ulceration	NA	33637	0.05% (17)
15	Mc Alhany et al. (1976) [37]	Burn	Antacid	24	29.1% (7)
16	Kahrom and Kahrom (2010) [36]	Opiate addiction	NA	35	100% (35)
17	Svanes et al. (1997) [35]	Smoking	NA	175	96% (168)