Table 1.

Main studies reporting the number of HCC cases in cohorts of PBC patients.

Study	Country	Study Period	n. PBC Patients	n. HCC Cases
Goldacre MJ [67]	UK	1963–1999	424	8
Floreani A [68]	Italy	1973–1996	175	4
Cavazza A [69]	Spain	NA	389	13
Cavazza A [69]	Italy	1973–2007	327	11
Jones D [70]	UK	1975–1995	667	16
Nijhawan P [71]	USA	1976–1985	1692	12
Shibuya A [72]	Japan	1980–1998	396	14
Howel D [73]	UK	1987–1994	769	7
Jackson H [74]	UK	1987–2002	930	7
Su C-W [75]	Taiwan	1985–2006	96	5
Deutsch M [76]	Greece	1987–2005	212	8
Kuiper EM [77]	The Netherland	1990–2007	375	9
Harada H [78]	Japan	1980–2009	2946	71
Trivedi PJ [79]	Global PBC	1959–2012	4565	123
Rong G [80]	China	1994–2014	1865	70
Braga MH [15]	Brasil	1992–2020	752	20
Zhang X-X [81]	China	2002–2013	1255	52
Cheng J-S [82]	Taiwan	2002–2015	2737	146
Boonstra K [83]	The Netherland	2008–2011	992	7