Figure 3.

Basal cell carcinoma—fibroepithelial (Pinkus) type. (A). Interconnected strands and clusters of basaloid cells enveloped by a fibrous stroma. When viewed from a three-dimensional standpoint, the tumor takes on the appearance of a honeycomb or sponge, characterized by thin epithelial septa, with the intervening spaces filled by stroma. Along the edges of the fenestrations, columnar cells are organized in a palisade formation. The tumor cells are positive for anti-CK AE1/AE3 (B) and anti-Bcl-2 antibodies (C).