Figure 4.

Basal cell carcinoma—adenoid and cystic type, infiltrative type, and micronodular type. (A). Adenoid and cystic type. Tumoral proliferation composed of plaques with pseudo-glandular appearance or with cystic degeneration. At the periphery of the plaques, nuclear palisading and artifact retraction of the surrounding stroma are observed. (B). Infiltrative type. Cords and trabeculae of basaloid-type tumor cells with basophilic, reduced cytoplasm, large nuclei, hyperchromatism, and a disposition resembling nuclear palisading at the periphery. The intertumoral stroma exhibits an abundant lymphoplasmacytic inflammatory infiltrate. (C). Micronodular type. Skin fragment covered by keratinized stratified squamous epithelium, presenting a tumoral proliferation in the underlying dermis composed of small, variable-shaped plaques with a solid, basaloid appearance.