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. 2024 Feb 19;13(4):1157. doi: 10.3390/jcm13041157

Table 2.

SER analysis of the included articles. When multiple follow-ups were conducted within the same study, the data are presented based on each follow-up period.

Authors Follow-Up
(m, Months)
TX
(n)
SVL
(n)
Baseline SER
(Mean ± SD) D
ΔSER at Follow-Up
(Mean ± SD) D
Absolute
Intergroup Change
Mean (SE), [95% CI] D
Relative Intergroup Change Relative Intragroup
Change
TX SVL TX SVL p TX SVL
Bao [20] 6 m HALs (54) (52) −2.70 ± 1.03 −2.46 ± 0.87 −0.10 ± 0.29 −0.34 ± 0.29 −0.24 (0.06), [−0.35 to −0.13] <0.001 * −70.59% 3.70% 13.82%
SALs (55) −2.31 ± 0.96 −0.17 ± 0.30 −0.17 (0.06), [−0.28 to −0.06] 0.004 * −50.00% 7.36%
Lam [18] 6 m DIMSs (79) (81) −2.97 ± 0.97 −2.76 ± 0.96 −0.13 ± 0.27 −0.37 ± 0.36 −0.24 (0.05), [−0.34 to −0.14] <0.001 * −64.86% 4.38% 13.41%
Liu X [19] 6 m CARE (52) (44) −2.67 ± 0.69 −2.56 ± 0.75 −0.38 ± 0.35 −0.47 ± 0.37 −0.09 (0.07), [−0.24 to 0.06] 0.224 −19.15% 14.23% 18.36%
Sankaridurg [30] 6 m HALs (54) (65) −3.47 ± 1.16 −3.37 ± 1.22 −0.20 ± 0.31 −0.27 ± 0.42 −0.07 (0.07), [−0.21 to 0.07] 0.312 −25.93% 5.76% 8.01%
Bao [20] 1 year HALs (54) (52) −2.70 ± 1.03 −2.46 ± 0.87 −0.27 ± 0.44 −0.81 ± 0.43 −0.54 (0.08), [−0.71 to −0.37] <0.001 * −66.67% 10.00% 32.93%
SALs (55) −2.31 ± 0.96 −0.48 ± 0.37 −0.33 (0.08), [−0.48 to −0.18] <0.001 * −40.74% 20.78%
Huang [26] 1 year DIMSs (30) (38) −2.84 ± 1.24 −2.60 ± 0.99 −0.79 ± 0.47 −1.07 ± 0.64 −0.28 (0.14), [−0.56 to −0.00] 0.049 * −26.17% 27.82% 41.15%
Lam [18] 1 year DIMSs (79) (81) −2.97 ± 0.97 −2.76 ± 0.96 −0.17 ± 0.44 −0.55 ± 0.36 −0.38 (0.06), [−0.51 to −0.25] <0.001 * −69.09% 5.72% 19.93%
Liu X [19] 1 year CARE (52) (44) −2.67 ± 0.69 −2.56 ± 0.75 −0.56 ± 0.46 −0.71 ± 0.39 −0.15 (0.09), [−0.32 to 0.02] 0.091 −21.13% 20.97% 27.73%
Liu J [27] 1 year DIMSs (2240) (2240) −2.88 ± 1.74 −2.85 ± 1.87 −0.50 ± 0.43 −0.77 ± 0.58 −0.27 (0.01), [−0.30 to −0.24] <0.001 * −35.06% 17.36% 27.02%
Long [28] 1 year DIMSs (90) (90) −3.82 ± 1.57 −3.75 ± 1.51 −0.51 ± 0.50 −0.85 ± 0.51 −0.34 (0.07), [−0.49 to −0.19] <0.001 * −40.00% 13.35% 22.67%
Rappon [23] 1 year DOTa (88) (93) −2.00 ± 0.93 −1.95 ± 1.02 −0.15 ± 0.39 −0.53 ± 0.46 −0.38 (0.06), [−0.51 to −0.25] <0.001 * −71.70% 7.50% 27.18%
DOTb (75) −1.85 ± 0.91 −0.23 ± 0.49 −0.30 (0.07), [−0.45 to −0.15] 0.001 * −56.60% 12.43%
Bao [29] 2 years HALs (54) (50) −2.70 ± 1.03 −2.44 ± 0.85 −0.66 ± 0.66 −1.46 ± 0.64 −0.80 (0.13), [−1.05 to −0.55] 0.001 * −54.79% 24.44% 59.84%
SALs (53) −2.28 ± 0.95 −1.04 ± 0.44 −0.42 (0.11), [−0.63 to −0.21] 0.002 * −28.77% 45.61%
Lam [18] 2 years DIMSs (79) (81) −2.97 ± 0.97 −2.76 ± 0.96 −0.38 ± 0.53 −0.93 ± 0.54 −0.55 (0.08), [−0.72 to −0.38] <0.001 * −59.14% 12.79% 33.70%
Liu J [27] 2 years DIMSs (735) (735) −3.00 ± 1.64 −2.92 ± 1.94 −0.88 ± 0.62 −1.23 ± 0.76 −0.35 (0.04), [−0.42 to −0.28] <0.001 * −28.46% 29.33% 42.12%
DIMSs (234) (234) −2.92 ± 1.54 −2.93 ± 1.99 −0.91 ± 0.45 −1.16 ± 0.45 −0.25 (0.04), [−0.33 to −0.17] <0.001 * −21.55% 31.16% 39.59%

TX, treatment group; SVL, single-vision lenses group; D, diopter; SER, spherical equivalent refraction; SD, standard deviation; SE, standard error; HALs, highly aspherical lenslets; SALs, slightly aspherical lenslets; DIMSs, defocus-incorporated multiple segments; CARE, cylindrical annular refractive element; DOT, diffusion optics technology (a and b are two models of DOT lenses, differing in diffusor element density); * denotes statistical significance.