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[Preprint]. 2024 Feb 15:2024.02.14.580352. [Version 1] doi: 10.1101/2024.02.14.580352

Figure 7. Cytokine secretion by BMDM infected with S. brasiliensis and treated with ML.

Figure 7.

a) BMDM cells were infected with S. brasiliensis yeast and treated with ML 20 and 40μg/mL for 24h. The interaction supernatant was collected and the cytokines TNF-α (ns: not significant; **p-value<0.005 when compared to untreated cells; ***p-value<0.0005 when compared to untreated cells; ****p-value<0.0001 when compared to untreated cells; #p-value<0.01 when compared to TRB treatment), IL-6 (ns: not significant; ***p-value<0.0005 when compared to untreated cells; ****p-value<0.0001 when compared to untreated cells), and IL-10 (ns: not significant; **p-value<0.005 when compared to untreated cells; ****p-value<0.0001 when compared to untreated cells; #p-value<0.0005 when compared to TRB treatment; ##p-value<0.0001 when compared to TRB treatment) were measured. b) BMDM cells were infected with S. brasiliensis yeast and treated with 20 and 40μg/mL for 48h. The interaction supernatant was collected and the cytokines TNF-α (ns: not significant; ****p-value<0.0001 when compared to untreated cells; #p-value<0.0005 when compared to TRB treatment; ##p-value<0.0001 when compared to TRB treatment), IL-6 (***p-value<0.001 when compared to untreated cells; (****p-value<0.0001 when compared to untreated cells; #p-value<0.005 when compared to TRB treatment; ##p-value<0.0001 when compared to TRB treatment), and IL-10 (ns: not significant; *p-value<0.05 when compared to untreated cells; **p-value<0.01 when compared to untreated cells; #p-value<0.05 when compared to TRB treatment; ##p-value<0.01 when compared to TRB treatment) were measured.