Extended Data Fig. 1: Transcriptomic analysis of the M2_IL4 and M2_GC macrophage populations.

a Expression of selected genes upregulated in M2_Cort and M2_Dex (n=3). b Volcano plot shows DEGs in M2_Cort relative to M0 (LogFC ≥ 1; FDR <0.05). Selected upregulated genes are highlighted blue, and downregulated in red. Some of the shared target genes between M2_IL4, M2_Dex, and M2_Cort are underlined. c Venn diagrams show differentially regulated pathways determined by QuSAGE in M2_IL4 and M2_Dex relative to M0 (p <0.05). d Differential pathways in M2 determined by QuSAGE as in Fig. 1d. Underlined are some of the pathways shared between M2_IL4, M2_Dex and M2_Cort (upregulated, blue; downregulated, red). e Genes from two pathways selectively repressed in M2_IL4 and M2_Dex are plotted as logFC±SD.