Table 2.
Demographic and clinical characteristics of patients diagnosed with respiratory syncytial virus.
| Pre-pandemic phase Jul 2013 – Mar 2020 N = 202,131 encounters | Post-emergence phase Apr 2021 – Jun 2023 N = 139,506 encounters | P-value | |
|---|---|---|---|
| Demographics | |||
| Age (months) | 6.87 (2.60– 17.48) | 11.89 (4.20–28.32) | < 0.001 |
| Age Category (%): • 0–90 days • 3–6 months • 6–12 months • 1–2 years • 2–4 years • 5+ years |
• 27.99% • 17.85% • 18.85% • 17.72% • 11.16% • 6.43% |
• 18.18% • 14.56% • 17.40% • 20.00% • 18.46% • 11.40% |
< 0.001 |
| Sex (% male) | 55.31% | 54.75% | 0.001 |
| Race (%) • White • Black • Asian • Pacific Islander • American Indian • Other • Multiple • Unknown |
• 58.61% • 18.43% • 2.80% • 0.53% • 0.29% • 10.31% • 1.49% • 7.54% |
• 57.03% • 19.15% • 3.30% • 0.80% • 0.30% • 11.21% • 2.72% • 5.49% |
< 0.001 |
| Ethnicity (%) • Hispanic or Latino • Not Hispanic or Latino • Unknown |
• 25.45% • 69.83% • 4.72% |
• 27.09% • 67.74% • 5.17% |
< 0.001 |
| Complex Chronic Condition (%) • 0–90 days • 3–6 months • 6–12 months • 1–2 years • 2–4 years • 5+ years |
16.84% • 12.14% • 8.91% • 11.89% • 16.67% • 29.22% • 52.76% |
11.69% • 11.98% • 6.46% • 7.74% • 9.45% • 13.21% • 25.46% |
< 0.001 • 0.50 • < 0.001 • < 0.001 • < 0.001 • < 0.001 • < 0.001 |
| Premature or Neonatal Complex Chronic Condition (%) | 3.10% | 2.57% | < 0.001 |
| Patient Type (%) • ED (Discharge) • ED & IP (ED Admit) • IP (Direct Admit) |
• 31.13% • 52.38% • 16.49% |
• 44.58% • 46.39% • 9.03% |
< 0.001 |
| Diagnostic Test (%) • Culture • Antigen • PCR • DNA Probe • SARS-CoV-2 Multi-Pathogen • Other/Unspecified Test • Multiple Tests • None (Clinical Diagnosis) |
• 0.28% • 20.29% • 1.09% • 0.27% • 0% • <0.01% • 0.44% • 77.62% |
• 0.13% • 4.65% • 2.63% • 0.04% • 31.04% • <0.01% • 0.29% • 61.22% |
< 0.001 |
| Clinical Characteristics | |||
| ED Patients Hospitalized (%) | 50.55% | 38.70% | < 0.001 |
| IP Length of Stay (days) | 3(2 – 5) | 2 (1 – 4) | < 0.001 |
| IP Length of Stay Category (%) • 0–1 day • 1–2 days • 2–4 days • 5–7 days • >7 days |
• 3.10% • 19.91% • 36.62% • 22.90% • 17.47% |
• 3.76% • 23.35% • 39.83% • 20.99% • 12.08% |
< 0.001 |
| IPs Admitted to the ICU or NICU (%) |
32.25% | 27.16% | < 0.001 |
| IPs Mechanically Ventilated (%) | 11.90% | 7.36% | < 0.001 |
| IPs Receiving ECMO (%) | 0.22% | 0.15% | < 0.001 |
| IP Hospital Mortality (%) | 0.24% | 0.16% | < 0.001 |
| Concurrent Influenza Diagnosis (%) | 2.19% | 1.38% | < 0.001 |
| Concurrent COVID-19 Diagnosis (%) | 0% | 2.73% | < 0.001 |
Medians (with interquartile ranges) are used to summarize distributions of continuous variables. ECMO, extracorporeal membrane oxygenation. ED, emergency department. IP, inpatient. ICU, intensive care unit. NICU, neonatal intensive care unit. PCR, polymerase chain reaction.