Table 2.
Differences between the RETAKO peripartum TTS and the literature peripartum TTS populations. The comparison included 6 patients from the RETAKO database and 32 from the literature review.
RETAKO Peripartum Takotsubo Syndrome (n = 6) | The Literature Peripartum Takotsubo Syndrome (n = 32) | p Value | ||
---|---|---|---|---|
Age (years) | 38.3 ± 2.3 | 34.2 ± 5.0 | 0.056 | |
Hypertension | 1 (16.7%) | 4 (15.4%) | 0.938 | |
Dislipidaemia | 1 (16.7%) | 1 (3.8%) | 0.242 | |
Diabetes Mellitus | 0 (0%) | 0 (0%) | n/a | |
Smoker/Ex-smoker | 1 (16.7%) | 1 (3.8%) | 0.098 | |
Obesity | 0 (0%) | 4 (15.4%) | 0.304 | |
TTS Trigger | Secondary form | 5 (83.3%) | 21 (80.8%) | 0.885 |
Symptoms | Angina | 1 (16.7%) | 8 (30.8%) | 0.489 |
Dyspnea | 5 (100%) | 19 (73.1%) | 0.197 | |
Palpitations | 2 (33.3%) | 1 (3.8%) | 0.026 | |
Syncope | 0 (0%) | 0 (0%) | ||
In-hospital complications |
Stroke | 1 (16.7%) | 1 (3.8%) | 0.242 |
Bleeding | 0 (0%) | 1 (3.8%) | 0.625 | |
Renal failure | 1 (16.7%) | 0 (0%) | 0.034 | |
Embolic events | 0 (0%) | 0 (0%) | ||
Maximum Killip status |
I | 2 (33.3%) | 11 (42.3%) | 0.016 |
II | 1 (16.7%) | 0 (0%) | ||
III | 2 (33.3%) | 1 (3.8%) | ||
IV | 1 (16.7%) | 14 (53.8%) | ||
LVEF | 38.8 ± 13.6 | 35 ± 11.2 | 0.475 | |
TTS pattern | Typical | 2 (33.3%) | 10 (38.5%) | 0.815 |
ECG abnormalities |
ST-segment elevation | 0 (0%) | 7 (26.9%) | 0.15 |
ST-segment depression | 1 (16.7%) | 2 (7.7%) | 0.497 | |
Initial T-wave inversion | 3 (50%) | 8 (30.8%) | 0.371 | |
Follow-up complications | 0 (0%) | 0 (0%) | ||
Deaths | 0 (0%) | 0 (0%) | ||
Follow-up | 1353.8 (296.2–2062.7) | 131.8 (27.7–180.0) | 0.003 |
Follow-up time is expressed as days (median) and interquartile range (IQR).