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. 2024 Feb 9;25(4):2127. doi: 10.3390/ijms25042127

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Photographs of the knee joint cartilage of rats with osteoarthritis induced by MIA. (A) The representative image indicates cartilage erosion with 3 mg/kg indomethacin, and 80 and 240 mg/kg SB were administered to MIA rats. The arrows indicate the cartilage degradation spot. (B) The macroscopic score. ### p < 0.001 vs. sham, ** p < 0.05 vs. control, *** p < 0.001 vs. control by a one-way analysis of variance, Dunnett’s test. INDO 3: indomethacin 3 mg/kg, MIA: monosodium-iodoacetate, SB: Scutellaria baicalensis.