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. 2024 Feb 23;10(8):eadj9945. doi: 10.1126/sciadv.adj9945

Fig. 1. Key spike mutations found in SARS-CoV-2 Omicron and XBB subvariants.

Fig. 1.

Spike amino acid substitutions in baseline sequences for BA.2, BA.5, BQ.1.1, XBB.1, XBB.1.5, and XBB.1.16 are depicted. XBB variants are recombinants between parental sequences BJ.1 (BA.2.10.1) and a sublineage of BA.2.75 (BM.1.1.1). BA.2 mutations compared with the ancestral WA1/2020 Spike are shown in black, and additional mutations relative to BA.2 are highlighted in colors corresponding to individual variants. Light gray shading indicates differences in prominent XBB lineages relative to the original recombinant founder. NTD, N-terminal domain; RBD, receptor binding domain.