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. 2024 Feb 8;25(4):2052. doi: 10.3390/ijms25042052

Figure 1.

Figure 1

Schematic representation of the main molecular pathways that become dysregulated in age-related sarcopenia. Abbreviations: Akt, protein kinase B; AMPK, AMP-activated protein kinase; 4E-BP1, eIF4E-binding protein 1; eNOS, endothelial nitric oxide synthase; FOXO, Forkhead box protein O; ATG, autophagy-related protein; LC3, microtubule-associated proteins 1A/1B light chain 3A; PI3K, phosphoinositide 3 kinase; S6K, S6 kinase; TFEB, transcription factor EB; TSC, tuberous sclerosis protein; UPS, ubiquitin proteasome system. Created with BioRender.com (accessed on 30 January 2024).