Table 1.
Fold change values of up- and down-regulated genes in U87 cells treated with CoCl2, 2 Gy, and CoCl2 + 2 Gy.
| Gene Expression Variations by qRT-PCR | ||||
|---|---|---|---|---|
| CoCl2 | 2 Gy | CoCl2 + 2 Gy |
||
| HRE regulated genes | hif-1α | 1.05 | 1.22 | 1.38 |
| glut-3 | 4.05 | 0.70 | 1.62 | |
| glut-1 | 2.10 | 0.94 | 1.92 | |
| eno-1 | 1.78 | 0.79 | 1.37 | |
| ldha | 1.43 | 1.08 | 1.41 | |
| pdk1 | 2.06 | 0.96 | 2.59 | |
| p21 | 2.16 | 1.29 | 2.38 | |
| lon | 1.30 | 1.07 | 1.16 | |
| lincRNA-p21 | 1.5 | 0.73 | 0.60 | |
| mir-210 | 1.36 | 0.99 | 1.01 | |
| mir-590 | 3.51 | 1.04 | 2.03 | |
| survivin | 0.38 | 0.71 | 0.52 | |
| livin | 0.76 | 0.49 | 0.48 | |
| Genes indirectly regulated by HIF-1α | bax | 1.43 | 1.38 | 0.95 |
| casp-9 | 0.7 | 0.95 | 0.68 | |
| bcl2 | 1.01 | 0.16 | 1.20 | |