Table 3.
Difference between coagulation markers during exacerbation and follow-up. Effect estimates and p-values. Mean and standard deviation (SD) during an exacerbation and in a stable phase. Mean differences with 95% Confidence Intervals (CIs) and p-values.
| Marker | Exacerbation, Mean ± SD | Follow-Up, Mean ± SD | Mean Difference (95% CI) | p-Value |
|---|---|---|---|---|
| MA (mm) | 69.06 ± 6.2 | 68.64 ± 6.6 | 0.41 (−1.42–+2.25) | 0.65 |
| R (min) | 5.56 ± 1.7 | 6.98 ± 8.8 | −1.42 (−3.70–+0.86) | 0.22 |
| Angle (degrees) | 70.63 ± 6.3 | 69.98 ± 5.6 | 0.64 (−0.92–+2.21) | 0.41 |
| Lys 30 (%) | 0.28 ± 0.7 | 0.24 ± 0.6 | 0.04 (−0.11–0.18) | 0.59 |
| Fibrinogen (µmol/L) | 11.23 ± 4.2 | 10.19 ± 2.6 | 1.05 (−0.76–+2.86) | 0.25 |
| Antithrombin (kIU/L) | 1.00 ± 0.2 | 1.02 ± 0.2 | −0.02 (−0.07–+0.02) | 0.31 |
| D-dimer (mg FEU/L) | 2.04 ± 2.5 | 2.40 ± 5.1 | −0.37 (−2.24–+1.51) | 0.69 |
| INR | 1.16 ± 0.4 | 1.08 ± 0.2 | 0.08 (−0.12–+0.27) | 0.42 |
| APTT (seconds) | 26.68 ± 5.2 | 30.96 ± 13.2 | −4.29 (−9.19–+0.62) | 0.08 |
Abbreviations: R, reaction time; MA, maximum amplitude; Lys 30, clot actively lysed after 30 min; INR, International Normalized Ratio; APTT, Activated Partial Thromboplastin Time.