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. 2024 Feb 23;19(2):e0295791. doi: 10.1371/journal.pone.0295791

Table 1. General characteristics of the patients.

Total patients n 790 UAS7 ≤6 n 342 UAS7 ≥7 n 448
Patient characteristics
Female sex * 602 (76.2%) 255 (74.5%) 347 (77.4%)
Median age in years (SD range) * 30 years (SD 11.6 range 68) 32 (SD 13, range 68) 29 (SD 10, range 66)
Age <49 years (%) 735 (93%) 311 (90.9%) 424 (94.6%)
BMI * 25 (SD 3.2 range 27) 25 (SD 3.2 range 22.5) 25 (SD 3.3 range 27)
Urticaria characteristics
CSU beginning (months)* 24 (SD 41.2 range 58.6) 21 (SD 50 range 58.6) 33 (SD 33 range 35.8)
CIU * 343 (43.4%) 91 (26.6%) 252 (56.2%)
Angioedema * 343 (43.4%) 91 252
UAS7 baseline * 26 (SD 7.8 range 35) 22 (SD 8 range 34) 26 (SD 7 range 35)
UAS7 final 10 (SD 10 range 42) 3 (SD 2 range 6) 18 (SD 8 range 35)
Comorbidities
NSAIDs reaction* 102 (12.9%) 38 (11.1%) 64 (14.2%)
Anxiety / Depression * 252 (31.9%) 81 (23.6%) 171 (38.1%)
Autoimmune disease * 118 (14.9%) 53 (15.4%) 65 (14.5%)
Paraclinical exams
Eosinophils * 124 (SD 133 range 1001) 125 (SD 141 range 1000) 124 (SD 126 range 1001)
Anti-TIPO IgG * 7.8 (SD 34.6 range 242) 7.5 (SD 33.9 range 211) 7.8 (SD 35.2 range 242)
C reactive protein * 0,3 (SD 1.3 range 14,2) 0.05 (SD 1.4 range 11.5) 0.05 (SD 1.25 range 14.2)
Atopy* 273 (34.6%) 117 (34.2%) 156 (34.8%)

Preselected variables for the prediction model are indicated with *. Median, range, and SD are presented because they do not have a normal distribution. UAS7 final; Represents UAS7 after using antihistamines at a conventional dose or four times the conventional dose. CIU: Chronic inducible urticaria.