Table 3. Construction of different models.
| Model #1: All variables | Model #2: All variables but age transformed | Model #3: statistically significance | Model #4: statistically significance plus biological plausibility |
|---|---|---|---|
| Age | Age (transformed) | Age (transformed) | Age (transformed) |
| Sex | Sex | // | Sex |
| Atopy | Atopy | // | // |
| Urticaria duration | Urticaria duration | Urticaria duration | Urticaria duration |
| Angioedema | Angioedema | Angioedema | Angioedema |
| CIU | CIU | // | // |
| Autoimmunity diseases | Autoimmunity diseases | // | Autoimmunity diseases |
| Anxiety and depression | Anxiety and depression | Anxiety and depression | Anxiety and depression |
| BMI | BMI | // | // |
| AINEs intolerance | AINEs intolerance | AINEs intolerance | AINEs intolerance |
| UAS7 at baseline | UAS7 at baseline | UAS7 at baseline | UAS7 at baseline |
| IgG anti-TPO | IgG anti-TPO | // | // |
| Blood eosinophils | Blood eosinophils | // | // |
| PCR | PCR | // | // |
BMI; body mass index. CIU; inducible chronic urticaria. UAS7 Urticaria Activity Score. Time: Duration of the urticaria. CRP: C-reactive protein. // variable no included in the model.