TABLE 4.
Alignment of Rpn11 to the conserved active-site cysteine in Ubp enzymes
| Protein | GenBank accession no. | Cys boxa | 
|---|---|---|
| Rpn11 | X79561/P43588 | 113 GFGCWLSSV 121 | 
| hUBP3 | Q92995 | 343 GNSCYLSSV 350 | 
| yUBP14 | P38237 | 351 GNSCYLNSV 359 | 
| hIsoT | U35116 | 332 GNSCYLNSV 340 | 
| yUBP8 | P50102 | 143 GSTCFMSSI 151 | 
| yUBP2 | Q01476 | 742 GNTCYLNSL 750 | 
The putative active-site cysteine is marked in boldface.