Skip to main content
. 2005 May 10;3(6):e176. doi: 10.1371/journal.pbio.0030176

Figure 1. Survival and Mutation of E. coli Mutants In Vivo after Starting Antibiotic Therapy.

Figure 1

Survival and mutation of ΔlacZ and lexA(S119A) mutants of E. coli ATCC 25922 in thighs of neutropenic mice at 24-h intervals after starting therapy with (A) ciprofoxacin or (B) rifampicin. Open circles and triangles correspond to the total cfu/thigh of the ΔlacZ and lexA(S119A) strains, respectively. Solid circles and triangles represent the number of drug-resistant ΔlacZ and lexA(S119A) cfu/thigh, respectively.