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Yoda1 effect on TMEM16A currents. (A) I-V relationships of control (Ctrl) in presence of 5 µM T16Ainh-A01 (T16Ainh) or 5 µM Yoda 1 plus 5 µM T16Ainh-A01 (T14Ainh + Yoda1). (B) The TMEM16A blocker T16Ainh-A01 significantly affected the currents recorded at both −80 mV (* p = 0.04) and +80 mV (* p = 0.03). Note that the addition of Yoda1 did not induce significant changes in the presence of T16inh-A01 both at −80 mV (p = 0.74; n = 5) and +80 mV (p = 0.6; n = 5).
