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. 2024 Feb 5;60(2):277. doi: 10.3390/medicina60020277

Table 1.

Clinical presentation.

Variable Total
N = 223
CFR ≤ 2
N = 91
CFR > 2
N = 117
p-Value IMR ≥ 25
N = 84
IMR < 25
N = 121
p-Value
NYHA class
None 105 (47.1) 41 (45.1) 51 (43.6) 0.79 36 (42.9) 54 (44.6) 0.19
I 29 (13.0) 10 (11.0) 19 (16.2) 7 (8.3) 22 (18.2)
II 63 (28.3) 27 (29.7) 34 (29.1) 27 (32.1) 33 (27.3)
III 21 (9.4) 11 (12.1) 10 (8.5) 12 (14.3) 9 (7.4)
IV 5 (2.2) 2 (2.2) 3 (2.6) 2 (2.4) 3 (2.5)
Shortness of breath 81 (37.5) 44 (48.4) 35 (29.9) 0.01 37 (44.0) 41 (33.9) 0.14
Chest pain 148 (68.5) 70 (76.9) 71 (61.7) 0.02 64 (77.1) 75 (62.5) 0.03
Palpitation/arrhythmia 34 (15.7) 16 (17.6) 17 (14.5) 0.55 19 (22.6) 13 (10.7) 0.02
Syncope 6 (2.8) 2 (2.2) 4 (3.4) 0.47 2 (2.4) 4 (3.3) 0.52
Prior cardiac arrest 5 (2.4) 1 (1.1) 4 (3.5) 0.27 2 (2.4) 3 (2.5) 0.67
CCS class
None 61 (27.4) 24 (26.4) 30 (25.6) 0.20 15 (17.9) 38 (31.4) 0.03
I 30 (13.5) 8 (8.8) 21 (17.9) 8 (9.5) 21 (17.4)
II 94 (42.2) 39 (42.9) 50 (42.7) 44 (52.4) 43 (35.5)
III 37 (16.6) 19 (20.9) 16 (13.7) 17 (20.2) 18 (14.9)
IV 1 (0.5) 1 (1.1) 0 (0.0) 0 (0.0) 1 (0.8)
Stable angina symptomatic 100 (44.8) 43 (47.3) 52 (44.4) 0.69 44 (52.4) 50 (41.3) 0.12
Unstable angina symptomatic 36 (16.1) 20 (22.0) 14 (12.0) 0.052 17 (20.2) 67 (79.8) 0.24

Data are presented as counts (percentages). CCS: Canadian Cardiovascular Society; CFR: coronary flow reserve; IMR: index of microcirculatory resistance; NYHA: New York Heart Association.