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. 2024 Jan 29;60(2):234. doi: 10.3390/medicina60020234

Table 2.

Meta-analysis of risk ratios for congenital anomalies after MMI/CMZ exposure during pregnancy.

Author, Year No. of Studies Included MMI/CMZ Control Crude RR, 95% CI for Congenital Anomalies Adjusted RR, 95% CI for Congenital Anomalies No. of Anomalies/1000 Live Births
Events/Total Events/Total
Agrawal et al., 2022 [33] 7 269/3521 340,801/5,364,080 RR 1.37; 95% CI 1.22–1.54 RR 1.28; 95% CI 1.06–1.54 17.2
Morales et al., 2021 [32] 4 RR 1.28; 95% CI, 1.06–1.54 17.8
Song et al., 2017 [34] 4 108/1395 83,426/1,461,088 RR 1.61; 95% CI 1.32–1.97
Li, H. et al., 2015 [24] 7 170/2993 83,490/1,463,996 RR 1.64; 95% CI 1.39–1.92
Li, X. et al., 2015 [35] 6 159/2662 83,450/1,462,586 RR 1.76; 95% CI 1.47–2.10