. 2024 Jan 29;60(2):234. doi: 10.3390/medicina60020234

Table 4.

Meta-analysis of risk ratios for congenital anomalies after exposure to both MMI/CMZ and PTU in pregnancy.

Author, Year	No. of Studies Included	MMI/CMZ + PTU	Control	Crude RR, 95% CI for Congenital Anomalies	Adjusted RR, 95% CI for Congenital Anomalies	No. of Anomalies/1000 Live Births
Author, Year	No. of Studies Included	Events/Total	Events/Total	Crude RR, 95% CI for Congenital Anomalies	Adjusted RR, 95% CI for Congenital Anomalies	No. of Anomalies/1000 Live Births
Agrawal et al., 2022 [33]	3	177/2126	254,049/4,318,697	RR 1.51; 95% CI, 1.14–1.99	RR 1.49; 95% CI, 1.20–1.84	31.4
Morales et al., 2021 [32]	3				RR 1.51, 95% CI 1.16–1.97	32.5
Song et al., 2017 [34]	2	30/285	83,333/1,446,588	RR 1.92; 95% CI, 1.32–2.81
Li, H. et al., 2015 [24]	2	30/285	83,333/1,446,588	RR 1.83; 95% CI 1.30–2.56
Li, X. et al., 2015 [35]	2	30/285	580/9475	RR 1.88; 95% CI 1.27–2.77