Table 2.
VAS for ocular tolerability average scores for both eyes by time and treatment.
| Treatment, Mean (SD) | ||||
|---|---|---|---|---|
| Visit Time (Days) | All Patients N = 30 |
Nextal N = 15 |
Respilac N = 15 |
p-Value a |
| Screening (day −3) | 25.0 (7.5) | 21.3 (5.4) | 28.8 (7.5) | 0.13 |
| Day 0 | 25.4 (7.6) | 21.5 (5.2) | 29.3 (7.6) | 0.07 |
| Day 7 | 14.4 (4.7) | 13.9 (4.2) | 14.9 (5.3) | 1.00 |
| Day 14 | 7.1 (3.4) | 7.5 (3.2) | 6.6 (3.5) | 0.78 |
| Day 21 | 3.5 (3.1) | 4.3 (3.2) | 2.7 (2.9) | 0.36 |
| Day 24 | 4.4 (2.5) | 4.2 (2.7) | 4.6 (2.3) | 1.00 |
| Overall | 13.3 (10.5) | 12.1 (8.4) | 14.5 (12.2) | 0.73 |
VAS: Visual analog scale. Main effects: treatment, p = 0.73; time p < 0.001; pre-treatment VAS p < 0.001; interaction: treatment × time, p < 0.001; a adjusted for multiple comparisons.