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. 2024 Feb 23;19(2):e0297467. doi: 10.1371/journal.pone.0297467

Table 4. Kinetic modeling of in-vitro drug release data.

Formulation Code R2 Value of “n” for Korsmeyer-Peppas
Zero-Order First-Order Higuchi Model Korsmeyer-Peppas Model
F 1 0.4946 0.9007 0.7631 0.6997 0.9826
2 0.4464 0.8909 0.7192 0.6865 0.9855
3 0.3057 0.2772 0.5871 0.6661 0.9836
4 0.215 0.1208 0.4722 0.6307 0.966
FP 1 0.2535 0.2628 0.5278 0.6501 0.8077
2 0.2697 0.2895 0.5404 0.6492 0.8222
3 0.7687 0.9603 0.955 0.7811 1.0078
4 0.667 0.9416 0.8964 0.7575 1.0051
G 1 0.8299 0.883 0.9207 0.7984 0.8632
2 0.7175 0.8115 0.9217 0.7794 0.8465
3 0.8443 0.9345 0.9765 0.8257 0.9222
4 0.6323 0.6833 0.8522 0.8291 0.8509
TABLETS F4 0.3156 0.3636 0.5985 0.6669 0.9861
FP4 0.7136 0.9536 0.9253 0.7826 1.0177
GP 0.9459 0.9596 0.9722 0.984 0.8081