Table 5.
Estimated p Values and Effect Sizes for Comparisons of Microglia Morphological Outcomes in the Hypothalamus Among Injury × Age Group Combinations from Generalized Linear Mixed Models With Negative-Binomial or Poisson Error Distributions
Comparison | No. microglia |
No. branches |
Branch length |
No. end-points |
||||
---|---|---|---|---|---|---|---|---|
p value | Effect size | p value | Effect size | p value | Effect size | p value | Effect size | |
Sham PND17 vs. TBI PND17 | 0.79 | 0.12 | 0.87 | 0.002 | 0.99 | 0.002 | 0.70 | 0.01 |
Sham PND17 vs. sham PND35 | 0.002 | 0.49 | <0.001 | 0.01 | <0.001 | 0.05 | <0.001 | 0.02 |
TBI PND17 vs. TBI PND35 | 0.11 | 0.27 | 0.51 | 0.004 | 0.11 | 0.02 | 0.50 | 0.01 |
Sham PND35 vs. TBI PND35 | 0.85 | 0.10 | 0.09 | 0.01 | 0.29 | 0.02 | 0.12 | 0.01 |
Statistical significance was achieved if p < 0.05, whereas biological significance was achieved if effect size >0.20. Bold values denote biologically important effects.
PND, post-natal day; TBI, traumatic brain injury.